Over the past decade, neural networks have been successful at making predictions from biological sequences, especially in the context of regulatory genomics. As in other fields of deep learning, tools have been devised to extract features such as sequence motifs that can explain the predictions made by a trained network. Here we intend to go beyond explainable machine learning and introduce SEISM, a selective inference procedure to test the association between these extracted features and the predicted phenotype. In particular, we discuss how training a one-layer convolutional network is formally equivalent to selecting motifs maximizing some association score. We adapt existing sampling-based selective inference procedures by quantizing this selection over an infinite set to a large but finite grid. Finally, we show that sampling under a specific choice of parameters is sufficient to characterize the composite null hypothesis typically used for selective inference-a result that goes well beyond our particular framework. We illustrate the behavior of our method in terms of calibration, power and speed and discuss its power/speed trade-off with a simpler data-split strategy. SEISM paves the way to an easier analysis of neural networks used in regulatory genomics, and to more powerful methods for genome wide association studies (GWAS).

网络流量动态的概括机器学习（ML）模型往往被认为是失去的原因。因此，对于每项新任务，我们通常都决心设计新模型并在模仿模型部署的环境中收集的特定于模型的数据集进行训练。这种方法本质上放弃了概括。但是，一个称为_transformer_的ML架构已在其他域中启用了以前无法想象的概括。如今，人们可以下载在大量数据集中预先训练的模型，而仅针对特定任务和上下文进行微调，以相对较少的时间和数据。这些微调模型现在是许多基准测试的最先进的。我们认为，这种进度可以转化为网络，并提出网络流量变压器（NTT），这是一个适合从数据包痕迹学习网络动态的变压器。我们的最初结果是有希望的：NTT似乎能够推广到新的预测任务和上下文。这项研究表明，尽管它需要许多未来的研究，但仍然有概括的希望。

我们通过与与前面令牌的局部相似度，通过调节从大语料库检索的文档块来增强自动回归语言模型。尽管使用25美元\时分，我们的检索增强型变压器（RetroCro）的检索增强型变压器（RetroCr）对GPT-3和侏罗纪-1获得了可比性的性能。微调后，复古表演转换为下游知识密集型任务，如问题应答。复古结合了冷冻BERT猎犬，一种可微分的编码器和块状的横向机制，以预测基于数量级的令牌，而不是训练期间通常消耗的数量。我们通常从头开始训练复古，还可以快速改造预先接受的变压器，通过检索，仍然达到良好的性能。我们的工作通过以前所未有的规模开辟了通过显式内存改进语言模型的新途径。

我们研究目标不当，这是强化学习（RL）中分布的概括失败。当RL代理商保留其功能过失但追求错误的目标时，就会发生目标失败失败。例如，代理商可能会继续有能力避免障碍，但要导航到错误的地方。相比之下，以前的工作通常集中在能力概括性失败上，因为代理在测试时间无法做任何明智的事情。我们将能力和目标泛化之间的这种区别形式化，提供了目标不当的第一个经验证明，并呈现了其原因的部分特征。

Biological systems and processes are networks of complex nonlinear regulatory interactions between nucleic acids, proteins, and metabolites. A natural way in which to represent these interaction networks is through the use of a graph. In this formulation, each node represents a nucleic acid, protein, or metabolite and edges represent intermolecular interactions (inhibition, regulation, promotion, coexpression, etc.). In this work, a novel algorithm for the discovery of latent graph structures given experimental data is presented.

The Government of Kerala had increased the frequency of supply of free food kits owing to the pandemic, however, these items were static and not indicative of the personal preferences of the consumers. This paper conducts a comparative analysis of various clustering techniques on a scaled-down version of a real-world dataset obtained through a conjoint analysis-based survey. Clustering carried out by centroid-based methods such as k means is analyzed and the results are plotted along with SVD, and finally, a conclusion is reached as to which among the two is better. Once the clusters have been formulated, commodities are also decided upon for each cluster. Also, clustering is further enhanced by reassignment, based on a specific cluster loss threshold. Thus, the most efficacious clustering technique for designing a food kit tailored to the needs of individuals is finally obtained.

Graph Neural Networks (GNNs) have shown great potential in the field of graph representation learning. Standard GNNs define a local message-passing mechanism which propagates information over the whole graph domain by stacking multiple layers. This paradigm suffers from two major limitations, over-squashing and poor long-range dependencies, that can be solved using global attention but significantly increases the computational cost to quadratic complexity. In this work, we propose an alternative approach to overcome these structural limitations by leveraging the ViT/MLP-Mixer architectures introduced in computer vision. We introduce a new class of GNNs, called Graph MLP-Mixer, that holds three key properties. First, they capture long-range dependency and mitigate the issue of over-squashing as demonstrated on the Long Range Graph Benchmark (LRGB) and the TreeNeighbourMatch datasets. Second, they offer better speed and memory efficiency with a complexity linear to the number of nodes and edges, surpassing the related Graph Transformer and expressive GNN models. Third, they show high expressivity in terms of graph isomorphism as they can distinguish at least 3-WL non-isomorphic graphs. We test our architecture on 4 simulated datasets and 7 real-world benchmarks, and show highly competitive results on all of them.

Prior works on improving speech quality with visual input typically study each type of auditory distortion separately (e.g., separation, inpainting, video-to-speech) and present tailored algorithms. This paper proposes to unify these subjects and study Generalized Speech Enhancement, where the goal is not to reconstruct the exact reference clean signal, but to focus on improving certain aspects of speech. In particular, this paper concerns intelligibility, quality, and video synchronization. We cast the problem as audio-visual speech resynthesis, which is composed of two steps: pseudo audio-visual speech recognition (P-AVSR) and pseudo text-to-speech synthesis (P-TTS). P-AVSR and P-TTS are connected by discrete units derived from a self-supervised speech model. Moreover, we utilize self-supervised audio-visual speech model to initialize P-AVSR. The proposed model is coined ReVISE. ReVISE is the first high-quality model for in-the-wild video-to-speech synthesis and achieves superior performance on all LRS3 audio-visual enhancement tasks with a single model. To demonstrates its applicability in the real world, ReVISE is also evaluated on EasyCom, an audio-visual benchmark collected under challenging acoustic conditions with only 1.6 hours of training data. Similarly, ReVISE greatly suppresses noise and improves quality. Project page: https://wnhsu.github.io/ReVISE.

Due to the high activation sparsity and use of accumulates (AC) instead of expensive multiply-and-accumulates (MAC), neuromorphic spiking neural networks (SNNs) have emerged as a promising low-power alternative to traditional DNNs for several computer vision (CV) applications. However, most existing SNNs require multiple time steps for acceptable inference accuracy, hindering real-time deployment and increasing spiking activity and, consequently, energy consumption. Recent works proposed direct encoding that directly feeds the analog pixel values in the first layer of the SNN in order to significantly reduce the number of time steps. Although the overhead for the first layer MACs with direct encoding is negligible for deep SNNs and the CV processing is efficient using SNNs, the data transfer between the image sensors and the downstream processing costs significant bandwidth and may dominate the total energy. To mitigate this concern, we propose an in-sensor computing hardware-software co-design framework for SNNs targeting image recognition tasks. Our approach reduces the bandwidth between sensing and processing by 12-96x and the resulting total energy by 2.32x compared to traditional CV processing, with a 3.8% reduction in accuracy on ImageNet.

Information on the grass growth over a year is essential for some models simulating the use of this resource to feed animals on pasture or at barn with hay or grass silage. Unfortunately, this information is rarely available. The challenge is to reconstruct grass growth from two sources of information: usual daily climate data (rainfall, radiation, etc.) and cumulative growth over the year. We have to be able to capture the effect of seasonal climatic events which are known to distort the growth curve within the year. In this paper, we formulate this challenge as a problem of disaggregating the cumulative growth into a time series. To address this problem, our method applies time series forecasting using climate information and grass growth from previous time steps. Several alternatives of the method are proposed and compared experimentally using a database generated from a grassland process-based model. The results show that our method can accurately reconstruct the time series, independently of the use of the cumulative growth information.